Material Drying
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Control of dissolution rate abnormality in PEOX calendering pharmaceutical films
Sorun Belirtisi
During PEOX calendering production of pharmaceutical films, the problem of large fluctuation in dissolution rate occurs.
Neden Analizi
Mainly due to the processing temperature deviating from the window +65-95°C, moisture content >0.5% exceeding the standard, and excessively long residence time.
Çözüm
Strictly control the temperature within the recommended range, fully dry the material to moisture content <0.1%, and shorten the residence time.
Temel Çıkarım
PEOX processing requires precise control of the three elements of temperature, humidity, and residence time.
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