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Material Drying 7 조회수

PCL slow biodegradation rate

문제 현상
The degradation cycle of PCL products is 3~4 years, which is too long and does not meet rapid degradation applications.
원인 분석
The semi-crystalline structure of PCL degrades slowly; high crystallinity slows hydrolysis; high molecular weight; environmental conditions; blending modification needs.;During on-site troubleshooting, verify item by item according to this mechanism, and avoid blindly adjusting the machine based solely on experience
해결 방법
①Blending with fast-degrading polymers; ②Crystallinity regulation; ③Molecular weight selection; ④Environmental condition optimization; ⑤Degradation test verification.;After adjustment, take continuous samples to verify the effect, and resume mass production only after confirming stability
핵심 요약
PCL slow degradation is an advantage for long-term implantation but also an obstacle for rapid applications; blending is a regulation means; tests verify the rate.;After confirming effectiveness, solidify the parameters and practices into the work instruction to prevent recurrence
PCL;degradation;slow rate;crystallization;blending;molecular weight

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