Thermoforming
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COC Blister Packaging Poor Heat Sealing
Fenómeno del problema
COC blister packaging has insufficient heat seal strength or deformation of the sealing area, the sampled sealing inspection of pharmaceutical packaging is unqualified, and the heat sealing window is narrow and difficult to adjust.
Análisis de la causa
The heat seal temperature matching window between the COC heat seal layer and the lidding material is narrow; too high temperature deforms the blister, too low temperature results in insecure sealing; sealing pressure and time, the three elements coupled, affect quality.
Solución
①Determine the heat sealing window of temperature, pressure and time by orthogonal tests; ②verify the matching of the lidding material and the COC blister material; ③calibrate the parallelism and temperature uniformity of the heat sealing mold; ④online leak detection of sealability.
Conclusión clave
COC heat sealing quality is three-parameter window management; material matching verification comes first; online leak detection is the last line of defense for pharmaceutical packaging.; After confirming effectiveness, fix the parameters and practices into the work instruction to prevent recurrence
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