Injection Molding
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COC Pre-filled Syringe Molding Defects
Problem Phenomenon
The barrel of COC pre-filled syringes shows uneven wall thickness, out-of-tolerance taper and appearance flow marks, and the sealing test with the rubber stopper is unqualified.
Cause Analysis
The deep-cavity thin-walled barrel has a long filling flow path, and the cooling of the melt front causes uneven wall thickness distribution; mismatch between mold temperature and injection curve produces flow marks; core pin temperature fluctuation affects the dimensional accuracy of the inner cavity.
Solution
①Follow the PDA recommended process: mold temperature 95~130℃, medium-high speed injection; ②staged injection to control the front state; ③independent temperature control of the core pin to stabilize inner cavity dimensions; ④linkage of sealing test and full dimensional inspection.
Key Takeaway
COC pharmaceutical packaging material molding is based on the PDA process window; temperature control of deep-cavity parts is the core of dimensional accuracy; pharmaceutical packaging material inspection must give equal weight to function and appearance.; After confirming effectiveness, fix the parameters and practices into the work instruction to prevent recurrence
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