Material Drying
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Control of dissolution rate abnormality in PEOX hot pressing pharmaceutical films
Problembeschreibung
During PEOX hot pressing production of pharmaceutical films, the problem of uneven dissolution rate occurs.
Ursachenanalyse
Mainly due to the processing temperature deviating from the window +70-90°C, moisture content >0.5% exceeding the standard, and shear heat accumulation.
Lösung
Strictly control the temperature within the recommended range, fully dry the material to moisture content <0.1%, and shorten the residence time.
Wichtigste Erkenntnis
PEOX processing requires precise control of the three elements of temperature, humidity, and residence time.
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