Material Drying
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Control of dissolution rate abnormality in PEOX hot pressing pharmaceutical films
Fenómeno do problema
During PEOX hot pressing production of pharmaceutical films, the problem of uneven dissolution rate occurs.
Análise das causas
Mainly due to the processing temperature deviating from the window +70-90°C, moisture content >0.5% exceeding the standard, and shear heat accumulation.
Solução
Strictly control the temperature within the recommended range, fully dry the material to moisture content <0.1%, and shorten the residence time.
Conclusão principal
PEOX processing requires precise control of the three elements of temperature, humidity, and residence time.
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